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The Merck Manual is continually updating the online version.
Updates of selected topics are posted about every two months. The following
updated topics have recently been posted:
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Human Immunodeficiency Virus Infection in Infants and Children
Selected excerpt from topic
Human Immunodeficiency Virus Infection in Infants and Children
"In the US, > 9300 cases have been reported in children and adolescents, representing only 1% of total cases. More than 90% of US children acquired the infection from their mother, either before or around the time of birth (vertical transmission). Most of the remainder (including children with hemophilia or other coagulation disorders) received contaminated blood or blood products. A few cases are the result of sexual abuse. Fewer than 5% of cases have no clear source."
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1. White DA, Scribner AN, Schulden JD, et al: Results of a rapid HIV screening and diagnostic testing program in an urban emergency department. Annals of Emergency Medicine Jul; 54(1):56-64, 2009.
2. Liang K, Gui X, Zhang YZ, Zhuang K, et al: A case series of 104 women infected with HIV-1 via blood transfusion postnatally: high rate of HIV-1 transmission to infants through breast-feeding. Journal of Infectious Diseases Sep 1; 200(5):682-686, 2009.
3. Khan M, Song X, Williams K, et al:
Evaluating adherence to medication in children and adolescents with HIV. Archives of Disease in Childhood Dec; 94(12):970-973, 2009.
4. Harris JR, Greene SK, Thomas TK, et al:
Effect of a point-of-use water treatment and safe water storage intervention on diarrhea in infants of HIV-infected mothers. Journal of Infectious Diseases Oct 15; 200(8):1186-1193, 2009.
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