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July 2010

Online Updates
The Merck Manual is continually updating the online version. Updates of selected topics are posted about every two months. The following updated topics have recently been posted:

Falls in the Elderly
Gait Disorders in the Elderly
Approach to the Care of Normal Infants and Children
Caring for Sick Children and Their Families
Perinatal Physiology
Perinatal Hematologic Disorders
Miscellaneous Infections in Infants and Children
Rheumatic Fever
Congenital Cardiovascular Anomalies
Congenital Renal and Genitourinary Anomalies
Inherited Disorders of Metabolism
Human Immunodeficiency Virus Infection in Infants and Children

View entire Table of Contents
featured_topic
Human Immunodeficiency Virus Infection in Infants and Children

Selected excerpt from topic

Human Immunodeficiency Virus Infection in Infants and Children


"In the US, > 9300 cases have been reported in children and adolescents, representing only 1% of total cases. More than 90% of US children acquired the infection from their mother, either before or around the time of birth (vertical transmission). Most of the remainder (including children with hemophilia or other coagulation disorders) received contaminated blood or blood products. A few cases are the result of sexual abuse. Fewer than 5% of cases have no clear source."

Selected Current Literature on Featured Topic
1. White DA, Scribner AN, Schulden JD, et al: Results of a rapid HIV screening and diagnostic testing program in an urban emergency department. Annals of Emergency Medicine Jul; 54(1):56-64, 2009.

2. Liang K, Gui X, Zhang YZ, Zhuang K, et al: A case series of 104 women infected with HIV-1 via blood transfusion postnatally: high rate of HIV-1 transmission to infants through breast-feeding. Journal of Infectious Diseases Sep 1; 200(5):682-686, 2009.

3. Khan M, Song X, Williams K, et al: Evaluating adherence to medication in children and adolescents with HIV. Archives of Disease in Childhood Dec; 94(12):970-973, 2009.

4. Harris JR, Greene SK, Thomas TK, et al: Effect of a point-of-use water treatment and safe water storage intervention on diarrhea in infants of HIV-infected mothers. Journal of Infectious Diseases Oct 15; 200(8):1186-1193, 2009.


Coming-Soon
Podcasts provide reviews of patient symptoms based on topics of the same title from The Merck Manual of Patient Symptoms. Click here to listen.

Featured podcasts

  • Fever in Infants and Children
  • Tremor

MinlQuiz
Each issue features a MinIQuiz relating to the recently updated topics. The MinIQuiz for this issue covers HIV Infection in Infants and Children, Falls in the Elderly, and Gait Disorders. Correctly answer the MinIQuiz questions (you can use The Merck Manual Online) to be entered in a drawing to win a print or a PDA download version of The Merck Manual.
(Click here for MinIQuiz entry rules.)

The presence of which of the following is not a criterion for the "severely symptomatic" clinical category (category C) of childhood HIV infection?

Cytomegalovirus infection onset before 1 month of age
Two or more episodes of pneumonia within a 2-year period
Extrapulmonary cryptococcosis
Lymphoma

Take the quiz!
Last month's MinIQuiz Answers & Winner

Last issue's MinIQuiz focused on Gram-Positive Cocci. Our winner is Dr. P. Van Laer, a pediatrician at Queen Paola Children's Hospital in Antwerp, Belgium.



View last issue's MinIQuiz answers.
 
   
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